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Newmatal CR
- Development stage
- Unknown
- Lead developer
- Binex
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Newmatal CR is a prolonged-release tablet formulation containing 200 mg of aceclofenac, developed and manufactured by Binex. Aceclofenac is a small molecule nonsteroidal anti-inflammatory drug (NSAID) and an analog of diclofenac. It acts by potently inhibiting the cyclooxygenase (COX) enzymes, specifically Prostaglandin G/H synthase 1 (COX-1) and Prostaglandin G/H synthase 2 (COX-2), thereby suppressing the synthesis of prostaglandins that mediate pain, fever, and inflammation. Newmatal CR is approved in South Korea for the relief of pain and inflammation associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, low back pain, and other inflammatory or painful disorders. The controlled-release formulation allows for once-daily dosing, offering improved patient compliance compared to conventional twice-daily aceclofenac formulations.
- Brand names
- Newmatal CR
- Other names
- Aceclofenac 200mgAceclofenac200mgAceclofenac-200mgNewmatal CR Tab.뉴마탈CR정
02
Targets
PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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