Drug intelligence / Profile preview

Next Science Oral Rinse

Development stage
Unknown
Lead developer
Next Science
Modality
Small Molecules
Administration
Topical
01

Overview

Next Science Oral Rinse is a specialized biofilm-disrupting solution designed to reduce the microbial load in the oral cavity, particularly targeting bacteria protected within biofilms. Developed by Next Science, the rinse utilizes the company proprietary Xbio technology, which is engineered to deconstruct the extracellular polymeric substance (EPS) matrix that shields bacteria from traditional antimicrobials and the host immune system. By breaking down this structural matrix, the rinse exposes the underlying microorganisms, facilitating their mechanical removal and destruction. It is primarily indicated for use as a pre-procedural or peri-operative rinse to minimize the risk of surgical site infections (SSIs) in patients undergoing oral, dental, or maxillofacial procedures. Unlike conventional mouthwashes that primarily target planktonic bacteria, this formulation is specifically optimized to address the structural integrity of established biofilms.

Brand names
Next Science Oral Rinse
Other names
Next Science Surgical Oral RinseNext Science Biofilm-Disrupting Oral Rinse

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