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NFIB siRNA
- Development stage
- Unknown
- Modality
- Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
NFIB siRNA is a research-grade small interfering RNA (siRNA) reagent designed to silence the expression of the Nuclear Factor I B-type (NFIB) gene via RNA interference (RNAi). NFIB is a transcription factor involved in various developmental processes and has been implicated in the progression of several cancers, including melanoma and estrogen receptor-negative breast cancer. By targeting the NFIB transcript for degradation, this siRNA reduces NFIB protein levels, allowing researchers to study its role in cell proliferation, apoptosis, and metastasis. It is primarily used as a laboratory tool and is available from various life science reagent suppliers such as Abbexa Ltd.
- Other names
- Nuclear Factor I B-type siRNANFI-B siRNANF1-B siRNANF-1-B siRNANF 1-B siRNATGGCA-binding protein siRNA
02
Targets
TLR7/8 (Toll-like receptor 7 and Toll-like receptor 8)NFIB (Nuclear factor I-B)
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