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Drug intelligence / Profile preview
NGC Children Cough Syrup
- Development stage
- Unknown
- Lead developer
- Sygen Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
NGC Children Cough Syrup is a combination pharmaceutical product developed by **Sygen Pharmaceuticals** for the symptomatic relief of cough and allergic respiratory conditions in pediatric patients. The formulation typically consists of **chlorpheniramine maleate**, an antihistamine, alongside expectorants such as **ammonium chloride** and **sodium citrate**. Chlorpheniramine acts as a competitive antagonist at the H1-receptor, effectively reducing symptoms like runny nose, sneezing, and watery eyes associated with hay fever and upper respiratory tract allergies. The expectorant components work to increase the volume and decrease the viscosity of respiratory tract secretions, facilitating the clearance of mucus. The product was originally part of the **Nigerian-German Chemicals (NGC)** portfolio before the company's assets were acquired by Sygen Pharmaceuticals.
- Brand names
- NGC Children Cough Syrup
- Other names
- NGC Children's Cough Syrup
02
Targets
HRH1 (Histamine H1 Receptor)mAChR (Muscarinic acetylcholine receptors)5-HT (Serotonin receptors)TRPM8 (Transient receptor potential cation channel subfamily M member 8)NaV (Voltage-gated sodium channels)
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