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NGM217 is an investigational long-acting antibody therapeutic developed by NGM Biopharmaceuticals for autoimmune diabetes. It binds an undisclosed target, so its precise molecular mechanism has not been publicly described, but it was positioned as an immunology-oriented biologic for diabetes treatment. NGM217 completed a Phase 1 clinical study in adults with autoimmune diabetes in 2020, where it was reported to be well tolerated, after which NGM Biopharmaceuticals suspended further activities on the program to prioritize other pipeline assets. NGM Biopharmaceuticals retained worldwide commercial rights.
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