Drug intelligence / Profile preview

niacinamide ascorbate

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

**Niacinamide ascorbate** is a 1:1 small-molecule complex of niacinamide and L-ascorbic acid, with molecular formula C12H14N2O7. It has been used as a vitamin-derived nutraceutical ingredient and has been described as a non-targeted antioxidant with potential radioprotective activity through mitigation of oxidative stress from ionizing radiation. A historical Canadian multivitamin product, Daily Balance Tab, contained niacinamide ascorbate and was cancelled from post-market status in 1998; this multivitamin product should not be considered a single-ingredient brand of niacinamide ascorbate. ([doi.usp.org](https://doi.usp.org/USPFCC/FCC_F101035_03_01.html))

Other names
Ascorbic acid nicotinamide complexL-ascorbic acid 3-pyridinecarboxamideL-ascorbic acid, compd. with 3-pyridinecarboxamideL-ascorbic acid, mixt. with nicotinamideMerpressNicastubinNicastubineNicoscorbineniacinamide ascorbateniacinamide L-ascorbatenicotinamide ascorbatenicotinamide L-ascorbateVitamin C-nicotinamide mixture
02

Targets

PARP1 (Poly (adp-ribose) polymerase 1)

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