Drug intelligence / Profile preview

nicomethanol hydrofluoride

Development stage
Phase 3
Lead developer
Pierre Fabre
Modality
Small Molecules
Administration
Topical
01

Overview

Nicomethanol hydrofluoride, frequently marketed under the trade name Fluorinol, is an organic fluoride compound specifically developed for oral hygiene and therapeutic dentistry. Unlike inorganic fluorides such as sodium fluoride, nicomethanol hydrofluoride acts as a high-affinity vector that facilitates the rapid and intense fixation of fluoride ions onto dental enamel. Developed by Pierre Fabre, the molecule's structure allows for superior fluoride uptake compared to traditional sources, leading to the formation of a robust fluorapatite layer. This process significantly enhances the remineralization of incipient carious lesions and strengthens the tooth's resistance to acid attacks from plaque bacteria. It is widely utilized in professional and consumer dental products, including toothpastes and mouthwashes, to prevent dental caries and alleviate tooth hypersensitivity.

Brand names
Fluorinol
Other names
nicomethanol fluorhydrate3-pyridinemethanol hydrofluoride3-pyridylmethanol hydrofluorideNicomethanolum hydrofluoridum

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