nicomorphine

Nicomorphine is a semi-synthetic opioid analgesic and the 3,6-dinicotinate ester of morphine. It acts as a strong opioid agonist and is two to three times as potent as morphine. Its side effect profile is similar to other opioids such as dihydromorphine and diamorphine. Nicomorphine was first synthesized in 1904 and patented under the brand name Vilan by Lannacher Heilmittel G.m.b.H. in Austria in 1957. It has been used for pain management (analgesia) but is classified as a Schedule I controlled substance in the United States due to its high potential for abuse and lack of accepted medical use there[1][5]. The drug exerts its effects primarily through agonism at mu-opioid receptors (and likely kappa- and delta-opioid receptors), leading to inhibition of nociceptive signal transmission[8][6].

Brand names

VilanSubellanGevilanMorZet

Other names

nicomorfinanicomorphinum