Drug intelligence / Profile preview

nicotinamide + papaverine + thiamine

Development stage
Unknown
Lead developer
NISSHAゾンネボード製薬
Modality
Small Molecules
Administration
Oral
01

Overview

Stomin A (ストミンA配合錠) is a combination pharmaceutical product developed and marketed by Zonnebodo Pharmaceutical in Japan for the treatment of tinnitus. It consists of three active components: nicotinamide (Vitamin B3), papaverine hydrochloride, and thiamine hydrochloride (Vitamin B1). Papaverine acts as a non-selective phosphodiesterase inhibitor, promoting smooth muscle relaxation and vasodilation to improve blood flow to the inner ear. Nicotinamide and thiamine serve as essential metabolic precursors and cofactors that support neuronal health and vascular integrity. The combination is specifically indicated for the relief of ringing in the ears (tinnitus).

Brand names
ストミンA配合錠Stomin A
Other names
Stomin A Combination Tablets
02

Targets

PDE (Phosphodiesterase family)

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