nicotinamide 8-bromo-adenine dinucleotide phosphate

Nicotinamide 8-bromo‐adenine dinucleotide phosphate (NA8BrADP) is a synthetic analog of nicotinamide adenine dinucleotide phosphate (NADP+), which is an essential cofactor in many enzymatic redox reactions. The compound features a brominated adenine moiety at the eighth position. As an NADP+ analog and member of the (5'→5')‐dinucleotides class of organic compounds, it may be used experimentally to probe or modulate NADP+-dependent biochemical pathways or enzyme activities. There are no approved therapeutic indications for this molecule; it is classified as experimental and primarily used in research settings[1][2][3].

Other names

Nicotinamide 8-bromo-adenine dinucleotide phosphateNicotinamide8-bromo-adenine dinucleotide phosphateNicotinamide-8-bromo-adenine dinucleotide phosphate[(2R,3R,4R,5R)-5-(6-amino-8-bromopurin-9-yl)-3-hydroxy-4-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl][(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxyoxolan -2 -yl]methyl phosphate(((2R,3R,4R,5R)-5-(6-amino–8-bromopurin–9–yl)–3–hydroxy–4-phosphonooxyoxolan–2–yl)methoxy-hydroxyphosphoryl)((2 R , 3 S , 4 R , 5 R ) – 5 – ( 3 – carbamoylpyridin –1 –ium –1 – yl ) – 3 , 4-dihydroxyoxolan -2 - yl ) methyl phosphate