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nicotine inhaler
- Development stage
- Unknown
- Lead developer
- Pfizer
- Modality
- Small Molecules
- Administration
- Inhalation, Oral Inhalation
01
Overview
The nicotine inhaler is a prescription smoking cessation aid consisting of a mouthpiece and a plastic cartridge that delivers 4 mg of nicotine from a porous plug containing 10 mg nicotine. Unlike cigarettes or asthma inhalers, the nicotine is absorbed primarily in the mouth and throat rather than the lungs. Users take frequent, short puffs over about 20 minutes per cartridge. The inhaler helps reduce nicotine withdrawal symptoms and cigarette cravings by providing controlled nicotine delivery without the harmful chemicals found in cigarette smoke. It's recommended for use as part of a comprehensive behavioral smoking cessation program.
- Brand names
- Nicotrol InhalerNicorette Inhaler
- Other names
- nicotine inhalation systemnicotine oral inhalation
02
Targets
α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)CHRNA7 (α7 nicotinic receptor)
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