nicotine mouth spray

Niconovum nicotine mouthspray (marketed under the brand name Zonnic) is an oromucosal (buccal) spray formulation of nicotine developed by Niconovum AB (a subsidiary of British American Tobacco) for nicotine replacement therapy (NRT). Delivering 1 mg of nicotine per actuation, the spray is administered to the oral cavity (specifically between the cheek and teeth/gum) to facilitate rapid absorption of nicotine through the buccal mucosa, providing fast relief from cravings and withdrawal symptoms in individuals undergoing smoking cessation. Nicotine acts as an agonist on nicotinic acetylcholine receptors (nAChRs) in both the central and peripheral nervous systems, mimicking the effects of tobacco-derived nicotine to ease the transition to smoking abstinence. The product has been evaluated in clinical trials, including Phase 3 studies, demonstrating rapid craving relief compared to other NRT formats like gum and lozenges.

Brand names

ZonnicZonnic Peppermint

Other names

Niconovum nicotine mouthspraynicotine mouthspraynicotine oral sprayZonnic mouth sprayZonnic oral spray