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nicotine patch
- Development stage
- Approved
- Lead developer
- Johnson & Johnson
- Modality
- Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Small Molecules
- Administration
- Transdermal
01
Overview
The nicotine patch is a transdermal delivery system that releases nicotine into the body through the skin. It is used as part of nicotine replacement therapy (NRT) to help people quit smoking by reducing withdrawal symptoms and cravings associated with stopping tobacco use. The patch provides a steady dose of nicotine over 16–24 hours and is applied daily to clean, dry, hairless skin on the upper chest, upper arm, or hip. Treatment typically involves gradually reducing the dose over several weeks to minimize withdrawal symptoms.[1][2][5]
- Brand names
- Nicoderm CQHabitrolNicotrol
- Other names
- nicotine transdermal patchnicotine skin patch
02
Targets
α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)CHRNA5 (Nicotinic acetylcholine receptor alpha-5 subunit)
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