Drug intelligence / Profile preview

Nicovape Q

Development stage
Unknown
Lead developer
Liber Pharmaceuticals
Modality
Small Molecules
Administration
Inhalation
01

Overview

Nicovape Q is an inhaled nicotine replacement therapy (iNRT) developed by Liber Pharmaceuticals. It is a closed-system nicotine liquid inhaler designed to deliver nicotine to the lungs via inhalation, providing a pharmacokinetic profile that more closely mimics the rapid nicotine delivery of combustible cigarettes compared to traditional nicotine replacement therapies (NRTs) such as patches or gums. The device aerosolizes a nicotine-containing solution which, upon inhalation, activates nicotinic acetylcholine receptors (nAChRs) in the central nervous system to alleviate cravings and withdrawal symptoms associated with smoking cessation. In September 2021, Nicovape Q became the first nicotine vaping product to be registered on the Australian Register of Therapeutic Goods (ARTG) as a prescription-only medicine for smoking cessation.

Brand names
Nicovape Q
Other names
NicovaperNicovape Q-Nicovaperinhaled nicotine replacement therapyiNRTnicotine-containing liquid inhaler
02

Targets

α4β2 nAChR (Nicotinic acetylcholine receptor alpha4 beta2 subtype)CHRNA2 (nAChR α2)CHRNA7 (α7 nicotinic receptor)

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