Drug intelligence / Profile preview

NIDB-3001

Development stage
Unknown
Lead developer
Discoveric Bio Beta
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

NIDB-3001 is a fully human κλ IgG antibody developed as an antimicrobial agent targeting Gram-negative outer membrane proteins. It is designed to interfere with essential processes in the outer membrane of Gram-negative bacteria, thereby inhibiting bacterial growth independently of host effector functions. The drug is being developed for the treatment of Gram-negative bloodstream infections, including those caused by *Escherichia coli* and *Klebsiella pneumoniae*. NIDB-3001 remains in the discovery or lead optimization phase and has not yet entered clinical trials. The developer is Discoveric Bio Beta (a part of Discoveric Bio Group), with Light Chain Bioscience also associated through partnership or technology platform[1][4][5].

02

Targets

OMPs (Essential outer membrane proteins of Gram-negative bacteria)

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