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Nikcell 1

Development stage: Unknown
Lead developer: Kian Immune Cell Company
Modality: CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies

Overview

Nikcell 1 is an allogeneic natural killer (NK) cell therapy developed by Kian Immune Cell Company, an Iranian biotechnology firm. The therapy consists of donor-derived, haploidentical NK cells designed to treat glioblastoma and various solid tumors. Its mechanism of action involves the innate cytotoxicity of NK cells, which recognize and eliminate malignant cells without prior sensitization, alongside cytokine-mediated immune activation that stimulates a broader anti-tumor response. The product is currently in Phase 2 clinical development, supported by the developer's established manufacturing processes for NK cell isolation from peripheral blood.

Brand names: Nikcell 1Nikcell1Nikcell-1
Other names: allogeneic NK cell therapy (Kian Immune Cell Company)

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