Drug intelligence / Profile preview

Nikzon

Development stage
Unknown
Lead developer
Genomma Lab
Modality
Small Molecules
Administration
Topical
01

Overview

Nikzon is an over-the-counter (OTC) topical combination treatment developed by Genomma Lab Internacional for the symptomatic relief of hemorrhoids and other anorectal disorders. It contains two primary active ingredients: phenylephrine hydrochloride, a sympathomimetic amine that acts as a vasoconstrictor to reduce swelling and inflammation by narrowing blood vessels in the affected area, and pramoxine hydrochloride, a local anesthetic that provides temporary relief from pain, itching, and burning. The formulation often includes soothing and protective agents such as aloe vera, glycerin, and petrolatum to help protect irritated tissue. It is typically applied topically to the affected area up to four times daily and is intended for external use only.

Brand names
Nikzon
02

Targets

ADRA1A (α1A)NaV (Voltage-gated sodium channels)

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