Drug intelligence / Profile preview

Ningbo Univ. HDAC6 compound 6c

Development stage
Preclinical
Lead developer
Ningbo University
01

Overview

Ningbo Univ. HDAC6 compound 6c: sourced facts only. name: "The leading compound 6c could direct bind to HDAC6, and selectively inhibits HDAC6 with a high affinity in vitro." [PMID:42763962]; target: "The leading compound 6c could direct bind to HDAC6, and selectively inhibits HDAC6 with a high affinity in vitro." [PMID:42763962]; developer: "Translational Medicine Center of Pain, Emotion and Cognition, Health Science Center, Ningbo University, Ningbo, 315211, China." [PMID:42763962]; stage: "Furthermore, 6c effectively prevented HDAC6-driven α-tubulin and Hsp90 deacylation, as well as cognitive impairments in Aβ1-42 oligomer-treated mice." [PMID:42763962]

02

Targets

HDAC6 (Histone deacetylase 6)

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