niosomal minocycline hydrochloride gel

Niosomal minocycline hydrochloride gel is an experimental local drug delivery system developed by researchers at Ain Shams University for the treatment of Stage II or Stage III periodontitis. The formulation utilizes niosomes—microscopic vesicles composed of non-ionic surfactants—as carriers to encapsulate minocycline hydrochloride, a broad-spectrum tetracycline antibiotic. This delivery system is designed to provide sustained release of the antibiotic directly into the periodontal pocket, aiming to maintain therapeutic concentrations for an extended period and improve penetration into periodontal tissues. It is typically used as an adjunct to non-surgical periodontal treatment, such as scaling and root planing, to reduce plaque index, gingival index, periodontal pocket depth, and improve clinical attachment levels.

Other names

Minocycline hydrochloride with noisome carrierMinocycline hydrochloride niosome gelNiosomal minocycline gelMinocycline hydrochloride niosomal gel