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Nipah Virus cVLP Vaccine
- Development stage
- Preclinical
- Lead developer
- AdaptVac
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
The Nipah Virus cVLP Vaccine is a prophylactic vaccine candidate developed by AdaptVac in collaboration with the VICI-Disease EU Horizon Europe consortium. The vaccine utilizes AdaptVac's proprietary capsid virus-like particle (cVLP) technology, which involves displaying Nipah virus antigens on a virus-like particle scaffold to mimic the structure of a virus and induce a robust, protective immune response. This approach is designed to prevent Nipah virus infection, a severe zoonotic disease characterized by high fatality rates and potential for outbreaks. As of 2024, the program is in the preclinical stage, entering GMP manufacturing with a Phase 1/2a clinical trial planned to commence in 2027.
- Other names
- Nipah virus capsid virus-like particle vaccine
02
Targets
NiV-G (Nipah virus attachment glycoprotein)
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