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Nitroketazine is an investigational small molecule drug being developed by Peking University Third Hospital for the treatment of amyotrophic lateral sclerosis (ALS). It is currently being evaluated in a Phase 2, multicenter, randomized, double-blind, placebo-controlled clinical trial (NCT04950647) to assess its safety and efficacy in slowing disease progression. The drug is administered orally in tablet form at doses of 600 mg or 1200 mg. While its specific biological target has not been publicly disclosed in clinical registries, the development program led by principal investigator Dongsheng Fan focuses on the drug's potential neuroprotective properties in ALS patients.
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