Drug intelligence / Profile preview

Niuxi Wenjing Tang

Development stage
Unknown
Lead developer
China Traditional Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Niuxi Wenjing Tang is a Traditional Chinese Medicine (TCM) formula used to treat gynecological disorders characterized by cold in the uterus and blood stasis. The formula is a modification of the classic Wenjing Tang, specifically incorporating *Achyranthes bidentata* (Niuxi) to enhance its ability to conduct blood downward and resolve stasis in the lower jiao. Its primary therapeutic actions include warming the meridians to dispel cold, nourishing the blood, and promoting circulation to alleviate pain. It is clinically indicated for conditions such as secondary amenorrhea, dysmenorrhea, and certain types of infertility. The pharmacological effects are attributed to a synergy of active compounds like ferulic acid, ligustilide, and cinnamaldehyde, which modulate the endocrine system and provide anti-inflammatory and analgesic benefits.

Brand names
Niushi Wenjing Decoction
Other names
牛膝温经汤Achyranthes Warm the Menses DecoctionNiuxi Wenjing Decoction
02

Targets

ESR1 (ERα)

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