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NK010

Development stage
Phase 1
Lead developer
Shanghai Enkai Cell Technology
Modality
CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

NK010 is a novel, non-genetically modified natural killer (NK) cell therapy developed from allogeneic peripheral blood mononuclear cells (PBMCs) of healthy donors. It is designed as an immune cell therapy with broad-spectrum antitumor activity, leveraging the high purity and activation receptor expression of NK cells to target diverse tumor types. Preclinical studies have demonstrated potent tumor-suppressing effects against ovarian cancer, liver cancer, acute myeloid leukemia (AML), and other solid tumors. The FDA has cleared clinical trials for NK010 in ovarian cancer, making it the first non-genetically modified allogeneic PBMC-derived NK cell therapy from China to receive such approval. Early-phase clinical development also includes lupus nephritis and other neoplasms. Developed by NK CellTech.

Other names
NK-010NK010NK 010

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