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NLY02 is a long-acting peptide agonist of the glucagon-like peptide-1 receptor (GLP-1R) developed by D&D Pharmatech and its subsidiary Neuraly. Designed for the treatment of metabolic disorders such as obesity, NLY02 mimics the action of the endogenous GLP-1 hormone to stimulate insulin secretion, inhibit glucagon release, and promote satiety. While its sibling candidate NLY01 is primarily focused on neurodegenerative conditions like Parkinson's disease, NLY02 is specifically optimized for metabolic indications. The compound has entered Phase 1 clinical development to evaluate its safety, tolerability, and pharmacokinetic profile in human subjects.
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