Drug intelligence / Profile preview

NM81

Development stage
Preclinical
Lead developer
Numab Therapeutics
Modality
Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous, Subcutaneous
01

Overview

NM81 is a potential first-in-class multispecific antibody being developed for the treatment of inflammatory bowel disease (IBD). Developed by Numab Therapeutics using its proprietary MATCH™ platform, NM81 is designed to simultaneously target multiple pathways involved in the pathogenesis of IBD, potentially offering improved efficacy over conventional monoclonal antibodies. The program is being advanced under a licensing and co-development agreement with Kaken Pharmaceutical, which is responsible for funding the preclinical and clinical development of the candidate through clinical proof of concept.

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