Drug intelligence / Profile preview

NNC0114-0006 + liraglutide

Development stage
Unknown
Lead developer
Novo Nordisk
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Peptides, Small Molecules
Administration
Intravenous, Subcutaneous
01

Overview

A combination therapy of **NNC0114-0006** (an anti-interleukin-21 monoclonal antibody) and **liraglutide** (a glucagon-like peptide-1 receptor agonist). NNC0114-0006 acts as an immunomodulatory agent, targeting and inhibiting interleukin-21 to reduce the autoimmune destruction of pancreatic beta cells. Liraglutide is a GLP-1 receptor agonist that enhances insulin secretion and improves beta-cell function. The combination is being developed as a potential disease-modifying intervention for **newly diagnosed type 1 diabetes**, aiming to preserve endogenous insulin production and beta cell function by both immune modulation and metabolic support[1][2][3][4].

Other names
anti-IL-21 + liraglutideanti-interleukin-21 monoclonal antibody + liraglutide
02

Targets

GLP1R (GLP-1R)IL21 (Interleukin-21)

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