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NNC0165-1562 + semaglutide is a **combination therapy** investigated for weight loss and metabolic diseases. **NNC0165-1562** is a peptide YY (PYY) analog, while **semaglutide** is a glucagon-like peptide 1 receptor (GLP-1R) agonist. This combination is hypothesized to have synergistic effects on appetite suppression and weight reduction. Both components are administered via once-weekly subcutaneous injection. The combination is developed by Novo Nordisk and has been studied in early phase trials in people with obesity or overweight to assess safety, pharmacokinetics, and efficacy.
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