Drug intelligence / Profile preview

NNC0165-1562 + semaglutide

Development stage
Unknown
Lead developer
Novo Nordisk
Modality
Peptides
Administration
Subcutaneous
01

Overview

NNC0165-1562 + semaglutide is a **combination therapy** investigated for weight loss and metabolic diseases. **NNC0165-1562** is a peptide YY (PYY) analog, while **semaglutide** is a glucagon-like peptide 1 receptor (GLP-1R) agonist. This combination is hypothesized to have synergistic effects on appetite suppression and weight reduction. Both components are administered via once-weekly subcutaneous injection. The combination is developed by Novo Nordisk and has been studied in early phase trials in people with obesity or overweight to assess safety, pharmacokinetics, and efficacy.

02

Targets

NPY2R (Neuropeptide Y receptor subtype 2)GLP1R (GLP-1R)

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