Drug intelligence / Profile preview

NNC0491-6075

Development stage
Phase 1
Lead developer
Novo Nordisk
Modality
Small Molecules
Administration
Subcutaneous, Intravenous
01

Overview

NNC0491-6075 is an investigational drug developed by Novo Nordisk for the treatment of dyslipidaemia and high cholesterol. It is currently in early-stage clinical development (Phase 1). The drug acts as an inhibitor of angiopoietin-like protein 3 (ANGPTL3), a target known to play a role in lipid metabolism. By inhibiting ANGPTL3, NNC0491-6075 aims to lower levels of fat in the blood, particularly non-HDL cholesterol, which may help reduce cardiovascular risk. The drug is being evaluated for safety and pharmacokinetics in healthy volunteers and individuals with elevated blood lipids through subcutaneous or intravenous administration.

Other names
NN-6491NN6491NN 6491NNC0491 6075NNC-0491 6075NNC 0491 6075
02

Targets

ANGPTL3 (Angiopoietin-like protein 3)

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