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NNC0491-6075 is an investigational drug developed by Novo Nordisk for the treatment of dyslipidaemia and high cholesterol. It is currently in early-stage clinical development (Phase 1). The drug acts as an inhibitor of angiopoietin-like protein 3 (ANGPTL3), a target known to play a role in lipid metabolism. By inhibiting ANGPTL3, NNC0491-6075 aims to lower levels of fat in the blood, particularly non-HDL cholesterol, which may help reduce cardiovascular risk. The drug is being evaluated for safety and pharmacokinetics in healthy volunteers and individuals with elevated blood lipids through subcutaneous or intravenous administration.
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