Drug intelligence / Profile preview

Noglux (Bioksan)

Development stage
Preclinical
Lead developer
Bioksan
Modality
Live Biotherapeutic Products → Microbiome Therapeutics, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Noglux is a multi-ingredient nutraceutical formulation developed by Bioksan Naturalmente Juntos, specifically designed for glycemic control and the management of prediabetes, metabolic syndrome, obesity, and metabolic dysfunction-associated steatotic liver disease (MASLD). The formulation contains a synergistic blend of active ingredients: white mulberry (*Morus alba*) leaf extract (standardized as Reducose, containing the alpha-glucosidase inhibitor 1-deoxynojirimycin), fenugreek (*Trigonella foenum-graecum*) extract (an AMPK activator), inulin (a prebiotic soluble fiber), *Lactiplantibacillus plantarum* A7 (a probiotic), niacin (vitamin B3), chromium, and zinc. Noglux acts by slowing carbohydrate digestion and sugar absorption, improving insulin sensitivity, reducing systemic inflammation (C-reactive protein), and mitigating liver fibrosis risk (as measured by FIB-4 scores).

Brand names
Noglux
Other names
Noguxwhite mulberry + fenugreek + inulin + niacin + chromium + zincwhite mulberry leaf extract + fenugreek + inulin + niacin + chromium + zinc
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)Sucrase-IsomaltaseHCAR2 (Hydroxycarboxylic acid receptor 2)INSR (Insulin receptor)

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