Drug intelligence / Profile preview

nojirimycine tetrazole

Development stage
Unknown
Modality
Small Molecules
01

Overview

Nojirimycine tetrazole is a synthetic small molecule belonging to the class of organic compounds known as tetrazoles. It is structurally related to nojirimycin and features a fused tetrazole ring. The compound acts as an inhibitor of glycogen phosphorylase (muscle form), an enzyme involved in glycogen breakdown. Nojirimycine tetrazole has been studied primarily as a research tool and experimental agent; it is not approved for clinical use in any country. Its main mechanism involves inhibition of muscle glycogen phosphorylase activity[1][3][4].

Other names
nojirimycine tetrazole(5R,6R,7S,8S)-5-(hydroxymethyl)-5H,6H,7H,8H-(1,2,3,4)tetrazolo(1,5-a)pyridine-6,7,8-triol(5R,6R,7S,8S)-5-(hydroxymethyl)-5H,6H,7H,8H-[1,2,3,4]tetrazolo[1,5-a]pyridine-6,7,-triolgluco-tetrazole
02

Targets

PYGM (Glycogen phosphorylase, muscle form)

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