norcyclobenzaprine

Norcyclobenzaprine (also known as desmethylcyclobenzaprine) is a major active metabolite of cyclobenzaprine, a muscle relaxant commonly marketed under the brand name Flexeril. Norcyclobenzaprine shares structural similarity with its parent compound and is formed in the body through demethylation. Both cyclobenzaprine and norcyclobenzaprine are potent antagonists of the serotonin 2a receptor. While cyclobenzaprine is used clinically to treat muscle spasms associated with acute musculoskeletal conditions, norcyclobenzaprine itself is not marketed as an independent pharmaceutical product but may contribute to the pharmacological effects and side effect profile of cyclobenzaprine therapy[9].

Other names

norcyclobenzaprinedesmethylcyclobenzaprine