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NORDBIOTIC OSTEODUO

Development stage: Preclinical
Lead developer: Nordic Biotic
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

NORDBIOTIC OSTEODUO is a probiotic dietary supplement developed by Nordic Biotic for the support of bone health and the prevention of osteoporosis, particularly in postmenopausal women. The formulation consists of two specific bacterial strains: Lactobacillus paracasei LPC100 (DSM 33793) and Lactobacillus plantarum LP140 (DSM 33804). It functions through the gut-bone axis, where the probiotic strains modulate the intestinal microbiota to enhance calcium absorption—potentially via the production of short-chain fatty acids (SCFAs)—and reduce systemic inflammation that contributes to bone resorption. Clinical data from a 12-month randomized, double-blind trial in early postmenopausal women demonstrated that the supplement helps maintain bone mineral density (as measured by DEXA scans of the lumbar spine) and preserves vitamin D levels.

Brand names: NORDBIOTIC OSTEODUO
Other names: OSTEODUO

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