norethisterone enanthate

Norethisterone enanthate (NET-EN) is a long-acting, injectable progestogen-only contraceptive. It is a prodrug of norethisterone, a synthetic second-generation progestin. When administered intramuscularly, typically at a dose of 200 mg every 8 weeks, it provides highly effective contraception by inhibiting ovulation, increasing the viscosity of cervical mucus to prevent sperm penetration, and altering the endometrium to discourage implantation. It is also frequently used in combination formulations, such as with estradiol valerate (e.g., Mesigyna or Compound Norethisterone Enanthate), for monthly administration. NET-EN is widely utilized globally for long-term birth control and is recognized for its high efficacy and reversible nature.

Brand names

NoristeratNorigest

Other names

norethindrone enanthatenorethisterone enantate庚酸炔诺酮