normal saline

**9% Saline (NS)** is a typographical error in clinical trial registries (such as NCT02477449) representing **0.9% Saline** (Normal Saline), which is a sterile, isotonic solution of sodium chloride (NaCl) in water. It contains 9 grams of sodium chloride per liter (0.9% w/v), matching the osmolarity of normal human extracellular fluid. Normal saline is widely used in clinical practice for intravenous hydration, extracellular fluid replacement, and as a vehicle or diluent for the administration of compatible intravenous drugs. In clinical trials, such as the Phase 1 study of istaroxime sponsored by Lee's Pharmaceutical, normal saline is frequently employed as an inert placebo or comparator control. It has no specific biological target or disease-modifying mechanism of action, and is not a therapeutic agent for acute heart failure.

Other names

0.9% sodium chloride0.9% sodium chloride solution9% Saline (NS)normal saline solutionphysiological salinesalinesaline solutionsodium chloride 0.9%sodium chloride 0.9% solution