Drug intelligence / Profile preview

normal saline (Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo)

Development stage
Unknown
Lead developer
University of Sao Paulo General Hospital
Modality
Small Molecules
Administration
Intravenous
01

Overview

0.9% physiological solution (normal saline) is an isotonic solution of sodium chloride in water, containing 9 g of NaCl per liter. It is widely used in clinical medicine for intravenous fluid replacement, electrolyte replenishment, and as a vehicle or diluent for the administration of other compatible drugs. In the context of the clinical trial NCT03715556, sponsored by the University of São Paulo General Hospital, it is used as an intravenous placebo (representing a 'liberal' heart rate control strategy) compared against amiodarone (a 'restrictive' strategy) in patients with sepsis and atrial fibrillation with high ventricular response.

Other names
0.9% physiological solution0.9% sodium chloride0.9% sodium chloride solutionisotonic salineisotonic sodium chloridenormal salinenormal saline solutionphysiological salinephysiological saline solutionphysiological salt solutionphysiological sodium chloride solutionsaline solutionsodium chloride 0.9%sodium chloride 0.9% solution

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