normal saline placebo

Normal saline placebo is an inert 0.9% sodium chloride solution used as a comparator in clinical trials. In the context of GlaxoSmithKline's Phase 2 study for chronic immune thrombocytopenia (ITP), it was administered intravenously to a control group to evaluate the efficacy and safety of belimumab. As a placebo, it contains no active pharmaceutical ingredients and has no biological target, serving solely to maintain the blinding of the study and provide a baseline for comparison against the active treatment arm. The solution is isotonic with human blood, making it a standard choice for intravenous control interventions in immunological and hematological research.

Other names

normal saline placebo-GlaxoSmithKline-chronic immune thrombocytopenia0.9% sodium chloride solutionsaline placebonormal saline