Drug intelligence / Profile preview

Normast MPS

Development stage
Unknown
Lead developer
Epitech
Modality
Small Molecules
Administration
Oral
01

Overview

Normast MPS is a food for special medical purposes (FSMP) developed and marketed by Epitech Group SpA. It contains a patented combination of micronized palmitoylethanolamide (PEA-m, 300 mg) and ultra-micronized palmitoylethanolamide (PEA-um, 600 mg). As an ALIAmide (Autacoid Local Injury Antagonist amide), its mechanism of action involves the modulation of non-neuronal immune cells, including mast cells, microglia, and astrocytes, to control neuroinflammation and pain sensitization. The product is specifically indicated for the management of Mixed Pain Syndrome (MPS), particularly neuropathic and mixed pain associated with osteo-articular conditions such as Complex Regional Pain Syndrome and Patellofemoral Pain, as well as broader neurodegenerative and neuroinflammatory conditions. It is administered orally and is commercially available in Italy.

Brand names
Normast MPSNORMAST MPS 20 COMPRESSE
Other names
palmitoylethanolamide micronized and ultra-micronizedPEA-m + PEA-um
02

Targets

GPR55 (G protein-coupled receptor 55)GPR119 (Glucose-dependent insulinotropic receptor)PPARA (Peroxisome proliferator-activated receptor alpha)

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