Drug intelligence / Profile preview

North-West Univ. MAO-A compound 2d

Development stage
Unknown
Lead developer
North-West University
01

Overview

North-West Univ. MAO-A compound 2d: sourced facts only. name: "The 4-chloroisatin substituted series (2a-d) showed exceptional MAO-A inhibition (2d: 0.040 ± 0.002 µM), while the unsubstituted, 5-, 6-, and 7-chloroisatin analogues (1a-e, 3a-c, 4a-b, and 5a-e) demonstrated high potency and selectivity toward MAO-B, the most active being 5d (0.018 ± 0.003 µM; selectivity index = 15 389)." [PMID:42603777]; target: "The 4-chloroisatin substituted series (2a-d) showed exceptional MAO-A inhibition (2d: 0.040 ± 0.002 µM), while the unsubstituted, 5-, 6-, and 7-chloroisatin analogues (1a-e, 3a-c, 4a-b, and 5a-e) demonstrated high potency and selectivity toward MAO-B, the most active being 5d (0.018 ± 0.003 µM; selectivity index = 15 389)." [PMID:42603777]; developer: "Centre of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa." [PMID:42603777]

02

Targets

MAOA (Monoamine oxidase A)

Beyond the preview

Go deeper on North-West Univ. MAO-A compound 2d.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on North-West Univ. MAO-A compound 2d.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call