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Nosis-Muscle-001 is an unnamed RNA-based therapeutic candidate being developed by Nosis Biosciences for the treatment of various muscle and musculoskeletal diseases. The program utilizes Nosis Bio's proprietary tissue-targeted delivery platform, which aims to deliver RNA medicines specifically to muscle tissues by targeting novel cell-surface receptors. As of 2025, the program is in the preclinical stage, specifically undergoing functional in vivo delivery validation to confirm the platform's ability to reach and modulate targets within muscle cells. The specific molecular targets and the exact RNA modality (e.g., siRNA, mRNA) have not yet been disclosed by the company.
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