Drug intelligence / Profile preview

NovaBone Putty

Development stage
Unknown
Lead developer
NovaBone
Modality
Nanoparticles → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems, Device-based Delivery → Drug Delivery Systems
Administration
Topical
01

Overview

NovaBone Putty is a synthetic, bioactive bone graft substitute and medical device used in orthopedic and dental surgery. It is composed of calcium phosphosilicate (CPS) bioactive glass particles in a bimodal size distribution, mixed with a binder of polyethylene glycol and glycerine. The putty is both osteoconductive, providing a physical scaffold for new bone growth, and osteostimulative, as it releases ions (calcium, phosphorus, and silica) that recruit and stimulate osteoblasts, upregulating genes associated with bone regeneration. It is fully resorbable and is indicated for filling bone defects in the extremities, spine, and cranio-maxillofacial regions, as well as for dental applications like periodontal repair.

Brand names
NovaBone Putty
Other names
calcium phosphosilicate puttyNovaBone Dental PuttyNovaBone CPS Putty

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