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Novartis Pharma LTA4H compound 3

Development stage
Preclinical
Lead developer
Novartis
01

Overview

Novartis Pharma LTA4H compound 3: sourced facts only. name: "Here, we describe the transformation of compound 2, a fragment-like hit, into the potent inhibitor of LTA4H 3." [PMID:38476002]; target: "Here, we describe the transformation of compound 2, a fragment-like hit, into the potent inhibitor of LTA4H 3." [PMID:38476002]; developer: "Global Discovery Chemistry, Biomedical Research, Novartis Pharma AG, 4002 Basel, Switzerland." [PMID:38476002]; stage: "Compound 3 exhibited exceptional selectivity and showed oral efficacy in a KRN passive serum-induced arthritis model in mice." [PMID:38476002]

02

Targets

LTA4H (Leukotriene A4 hydrolase)

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