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NOVO118 is a preclinical small-molecule inhibitor developed by Novoron Bioscience. It is being advanced for Alzheimer's drug discovery, specifically targeting LRP1-mediated tau spread. The goal for NOVO118 is to generate more predictive, human-relevant data to de-risk drug candidates prior to IND-enabling studies, addressing the high failure rate of Alzheimer's drugs developed with traditional models.
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