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Drug intelligence / Profile preview
novoleucel
- Development stage
- Preclinical
- Lead developer
- Cbio
- Modality
- Patient-derived iPSCs → iPSCs → Pluripotent Stem Cells → Stem Cell Therapies → Cell Therapies, Hematopoietic Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies, CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Mesenchymal Stem Cells → Adult Stem Cells → Stem Cell Therapies → Cell Therapies, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Tumor-Infiltrating Lymphocytes (TILs) → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
Novoleucel is a novel, broad-acting T cell therapy under development for the treatment of cervical cancer. It is being developed as an autologous T cell therapy, which involves collecting a patient’s own T cells, genetically modifying or expanding them to enhance their anti-tumor activity, and then reinfusing them into the patient. The approach aims to harness and direct the immune system to target and destroy cancer cells more effectively. Novoleucel has completed preclinical development for cervical cancer and is advancing toward clinical trials[4].
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