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Novospray
- Development stage
- Preclinical
- Administration
- Topical
01
Overview
**Novospray** is an investigational, locally administered artificial-saliva oral spray developed at the Academic Centre for Dentistry Amsterdam for symptomatic relief of xerostomia, including dry mouth associated with Sjögren's syndrome. It was evaluated in a randomized crossover study against a placebo spray. The publicly available trial materials describe the investigational artificial-saliva spray as containing an ingredient derived from chicken eggs, but do not publicly identify its complete composition or a defined molecular target. Its intended action is physical and symptomatic: supplementing oral moisture and improving oral comfort rather than restoring salivary-gland function or modifying the autoimmune pathology of Sjögren's syndrome. ([onderzoekmetmensen.nl](https://onderzoekmetmensen.nl/en/node/20248/pdf))
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