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NR3C4-targeted Nanoparticles is a preclinical-stage targeted drug delivery system developed by Prosemble for the treatment of ovarian cancer. The platform utilizes nanoparticles engineered to specifically target the NR3C4 receptor, also known as the Androgen Receptor, which is expressed in certain ovarian tumors. By leveraging this targeting mechanism, the nanoparticles are designed to deliver therapeutic payloads directly to cancer cells, potentially enhancing treatment efficacy while minimizing systemic exposure and associated side effects. The development is currently in the preclinical phase, with the company exploring its utility in NR3C4-expressing malignancies.
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