Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
NRG Therapeutics mPTP backup series
- Development stage
- Preclinical
- Lead developer
- NRG Therapeutics
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
NRG Therapeutics' mPTP backup series consists of structurally differentiated small-molecule inhibitors targeting the mitochondrial permeability transition pore (mPTP). These compounds are being developed as follow-on assets to the company's lead candidate, NRG5051, for the treatment of neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS), Motor Neuron Disease (MND), and Parkinson's disease. Designed to be orally bioavailable and CNS-penetrant, these molecules aim to provide neuroprotection by preventing mPTP opening, a process linked to mitochondrial dysfunction, cell death, and neuroinflammation. The program is currently in the discovery and preclinical stages of development.
- Other names
- NRG backup seriesmPTP inhibitors (backup series)
02
Targets
SpA (Staphylococcal protein A)
Beyond the preview
Go deeper on NRG Therapeutics mPTP backup series.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on NRG Therapeutics mPTP backup series.