Drug intelligence / Profile preview

NSA-789

Development stage
Phase 1
Lead developer
Pfizer
Modality
Small Molecules
Administration
Oral
01

Overview

NSA-789 is an orally administered small molecule drug that was developed by Wyeth and later Pfizer for the treatment of cognitive impairment associated with Alzheimer's disease and schizophrenia. It was classified as both an antidementia and antipsychotic agent, but its precise mechanism of action remains undefined. The drug reached Phase 1 clinical trials for both Alzheimer's disease and schizophrenia, including studies in healthy volunteers, but development was discontinued after these early-stage trials[1][2][3]. No orphan drug status or FDA approval was granted.

Other names
NSA 789NSA789NSA-789

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