Drug intelligence / Profile preview

NSC61610

Development stage
Preclinical
Lead developer
Biotherapeutics
Modality
Small Molecules
Administration
Oral
01

Overview

NSC61610 is an orally active, small molecule lanthionine synthetase C-like 2 (LANCL2) ligand and activator. Developed by Biotherapeutics, NSC61610 acts as an immunomodulator that targets the LANCL2 pathway to suppress inflammation. In preclinical models, NSC61610 has demonstrated therapeutic efficacy against influenza A virus infection and inflammatory bowel disease (IBD) by down-modulating pulmonary and colonic inflammation, reducing pro-inflammatory cytokines (such as TNF-alpha and MCP-1), and promoting IL-10-mediated regulatory responses.

Other names
1-N,4-N-bis[3-(1H-benzimidazol-2-yl)phenyl]benzene-1,4-dicarboxamideN1,N4-bis(3-(1H-benzo[d]imidazol-2-yl)phenyl)terephthalamideN1,N4-bis[3-(1H-benzimidazol-2-yl)phenyl]benzene-1,4-dicarboxamideN1,N4-bis[3-(1H-benzimidazol-2-yl)phenyl]terephthalamide
02

Targets

LANCL2 (Lanthionine synthetase C-like protein 2)

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