Drug intelligence / Profile preview

NTX1107

Development stage
Preclinical
Lead developer
Nectin Therapeutics
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

NTX1107 is an antibody-drug conjugate (ADC) being developed by Nectin Therapeutics for the treatment of solid and hematological malignancies. It is designed to deliver a cytotoxic payload directly to tumor cells expressing a specific antigen, which is currently undisclosed by the developer (though some industry reports suggest a target within the nectin or nectin-like family). By combining the targeting specificity of a monoclonal antibody with the potent cell-killing ability of a cytotoxic agent, NTX1107 aims to overcome resistance in various cancers. The program is currently in the IND-enabling stage of development, representing a key component of Nectin Therapeutics' pipeline of next-generation cancer therapies.

02

Targets

NECTIN2 (Nectin cell adhesion molecule 2)

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